Memory loss on account of plaque in the brain is a very serious condition called Alzheimer’s. The research focuses on understanding the role of amyloid, the protein that builds up in the brain to form plaques.

A new avenue of research has been opened now. On studying mice, they realised that immune system protects the brain. Instead these begin to consume a nutrient called arginine, an amino acid. If this consumption is blocked by a drug, plaque formation is prevented.That halts the memory loss. The study will have to be extended to the humans.

The arginine-blocking drug used is difluromethylornithine (DFMO).

Arginine is produced in cell-division, healing and immune responses. It is found in food including dairy  products, meat,nuts. The blood brain barrier regulates the flow of arginine.

This study is published in the Journal of Neuroscience and was led by Matthew Kan in Professor Colton’s lab.